Methacholine challenge testing: comparative pharmacology
نویسندگان
چکیده
منابع مشابه
Methacholine challenge testing in Reserve Officer Training Corps cadets.
STUDY OBJECTIVE To determine the prevalence of positive results for methacholine challenge tests in asymptomatic Reserve Officer Training Corps (ROTC) cadets with no history of asthma. DESIGN Prospective, blinded cohort comparison study. SETTING Pulmonary diseases clinic in a US Army tertiary-care medical center. PATIENTS One hundred three college students who were undergoing a physical e...
متن کاملConflicting methacholine challenge tests.
An 11-year-old boy experienced almost daily wheezing, dyspnea on exertion, and sleep perturbation because of cough. In addition, nadir peak expiratory flow (PEF) was below 100 L/min, which was 30% of predicted (328 L/min),1 compatible with severe persistent asthma.2 After the initiation of therapy with 180 g of albuterol 3 times per day, the patient’s domiciliary PEF rose to 200 L/min and his s...
متن کاملERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests.
This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test. There are notable changes from prior recommendations in order to accommodate newer delivery devices. Rather than basing the test result upon a methacholine concentration (provocative concentration (PC20) causing a 20% fall in forced expirato...
متن کاملMethacholine challenge: test-shortening procedures.
STUDY OBJECTIVES Validation of test-shortening procedures for the 2-min tidal breathing methacholine challenge method. DESIGN Retrospective chart review. SETTING Tertiary-care university clinical pulmonary function laboratory. PATIENTS One thousand subjects aged 10 to 85 years (mean +/- SD, 44.5 +/- 16.0 years), 44.5% male, referred for methacholine challenge. INTERVENTION Two-minute ti...
متن کاملDevelopment of a methacholine challenge method to minimize methacholine waste.
BACKGROUND The standard 2-min tidal breathing methacholine challenge utilizes 3 mL to produce an output of 0.26 mL per 2 min, resulting in a substantial amount of methacholine being discarded. OBJECTIVE To develop a method with reduced methacholine waste and to compare it to the standard method. METHODS Twelve subjects with mild, well-controlled asthma volunteered for this investigation. Th...
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ژورنال
عنوان ژورنال: Journal of Asthma and Allergy
سال: 2018
ISSN: 1178-6965
DOI: 10.2147/jaa.s160607